Lawrence G Lum Selected Research

Adenocarcinoma

9/2004	Anti-CD3 x anti-HER2 bispecific antibody effectively redirects armed T cells to inhibit tumor development and growth in hormone-refractory prostate cancer-bearing severe combined immunodeficient beige mice.
3/2004	Redirected T-cell cytotoxicity to epithelial cell adhesion molecule-overexpressing adenocarcinomas by a novel recombinant antibody, E3Bi, in vitro and in an animal model.

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Lawrence G Lum Research Topics

Disease

49	Neoplasms (Cancer) 01/2022 - 09/2001
9	Breast Neoplasms (Breast Cancer) 01/2022 - 08/2003
6	Hematologic Neoplasms (Hematological Malignancy) 01/2021 - 04/2005
5	Prostatic Neoplasms (Prostate Cancer) 01/2015 - 09/2004
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2021 - 01/2012
4	Multiple Myeloma 01/2020 - 04/2005
3	Neoplasm Metastasis (Metastasis) 11/2016 - 06/2011
3	Glioma (Gliomas) 02/2016 - 05/2012
3	Infections 09/2015 - 07/2012
3	Graft vs Host Disease (Graft-Versus-Host Disease) 01/2015 - 04/2009
3	Myocardial Infarction 06/2008 - 01/2004
2	Colorectal Neoplasms (Colorectal Cancer) 01/2022 - 01/2006
2	Fever (Fevers) 01/2017 - 09/2015
2	Non-Hodgkin Lymphoma (Lymphosarcoma) 06/2013 - 04/2005
2	Carcinoma (Carcinomatosis) 03/2006 - 01/2005
2	Adenocarcinoma 09/2004 - 03/2004
1	Critical Illness (Critically Ill) 01/2022
1	COVID-19 01/2022
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	T-Cell Lymphoma (Lymphoma, T Cell) 11/2021
1	Anaplastic Large-Cell Lymphoma (Ki 1 Lymphoma) 11/2021
1	Seroma 11/2021
1	Triple Negative Breast Neoplasms 01/2021
1	Lung Neoplasms (Lung Cancer) 08/2020
1	Asthma (Bronchial Asthma) 10/2016
1	Inflammation (Inflammations) 10/2016
1	Pleural Effusion (Pleural Effusions) 01/2016
1	Mucositis 09/2015
1	Gastroenteritis 01/2015
1	Viremia 01/2015
1	Fibrosis (Cirrhosis) 11/2014
1	Hypoxia (Hypoxemia) 11/2014
1	Stevens-Johnson Syndrome (Lyell's Syndrome) 11/2014
1	Lymphoma (Lymphomas) 06/2013
1	Glioblastoma (Glioblastoma Multiforme) 02/2013
1	Neuroectodermal Tumors (Neuroectodermal Tumor) 12/2012

Drug/Important Bio-Agent (IBA)

19	CytokinesIBA 11/2021 - 09/2001
13	Bispecific AntibodiesIBA 01/2022 - 01/2004
11	AntigensIBA 01/2022 - 01/2004
5	AntibodiesIBA 01/2022 - 12/2011
5	Monoclonal AntibodiesIBA 12/2021 - 01/2005
5	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2018 - 09/2004
4	Interleukin-2 (IL2)IBA 01/2018 - 03/2004
3	Chimeric Antigen ReceptorsIBA 01/2021 - 11/2015
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022 - 09/2004
2	Therapeutic UsesIBA 12/2021 - 01/2006
2	ChemokinesIBA 03/2021 - 01/2021
2	Conditioned Culture MediaIBA 03/2021 - 01/2013
2	Pharmaceutical PreparationsIBA 01/2021 - 01/2012
2	Gemcitabine FDA Link 01/2021 - 02/2013
2	Immunoglobulin G (IgG)IBA 01/2021 - 01/2015
2	Interleukin-12 (IL 12)IBA 01/2018 - 05/2015
2	Biological ProductsIBA 11/2016 - 11/2014
2	Interleukin-10 (Interleukin 10)IBA 07/2014 - 01/2013
2	VaccinesIBA 05/2013 - 05/2012
1	Antiviral Agents (Antivirals)IBA 01/2022
1	Estrogens (Estrogen)FDA Link 01/2022
1	Biomarkers (Surrogate Marker)IBA 11/2021
1	Peptide Hydrolases (Proteases)FDA Link 11/2021
1	Granzymes (Granzyme)IBA 11/2021
1	Peptides (Polypeptides)IBA 10/2021
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2021
1	Cisplatin (Platino)FDA LinkGeneric 01/2021
1	Fluorouracil (Carac)FDA LinkGeneric 01/2021
1	ATP-Binding Cassette Transporters (ABC Transporters)IBA 01/2021
1	thiamine triphosphorate (TTP)IBA 10/2020
1	Dihydrotachysterol (AT 10)IBA 08/2020
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Anti-Bacterial Agents (Antibiotics)IBA 01/2017
1	FluoroquinolonesIBA 01/2017
1	Small Interfering RNA (siRNA)IBA 10/2016
1	PolyethyleneimineIBA 10/2016
1	Transferrin (beta 2 Transferrin)IBA 10/2016
1	NestinIBA 02/2016
1	Melphalan (Alkeran)FDA LinkGeneric 09/2015
1	Neoplasm Antigens (Tumor Antigens)IBA 12/2014
1	SERPIN-B5 (maspin)IBA 11/2014
1	Chemokine CCL2 (Monocyte Chemoattractant Protein 1)IBA 07/2014
1	IpilimumabIBA 07/2014
1	EnzymesIBA 06/2013
1	ImmunosorbentsIBA 06/2013
1	AndrogensIBA 05/2013
1	epidermal growth factor receptor VIIIIBA 02/2013
1	Temozolomide (Temodar)FDA LinkGeneric 02/2013
1	Dinoprostone (PGE2)FDA Link 02/2013
1	GD2 gangliosideIBA 12/2012

Therapy/Procedure

19	Therapeutics 12/2021 - 09/2004
16	Immunotherapy 01/2022 - 01/2006
6	Drug Therapy (Chemotherapy) 01/2022 - 09/2015
6	Stem Cell Transplantation 05/2016 - 11/2010
3	Hematopoietic Stem Cell Transplantation 01/2016 - 11/2014
2	Cell- and Tissue-Based Therapy (Cell Therapy) 08/2020 - 01/2012
1	Immunomodulation 01/2022
1	Breast Implants (Breast Implant) 11/2021
1	Injections 03/2021
1	Cell Transplantation 02/2015
1	Transplantation 01/2015
1	Prostatectomy (Retropubic Prostatectomy) 05/2013
1	Radiotherapy 05/2013
1	Castration 05/2013